Title : Metabolomics [NEW TOPIC PAGE]
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Metabolomics [NEW TOPIC PAGE]
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Gender-specific association of early age-related macular degeneration with systemic and genetic factors in a Japanese population.  Scientific reports 2018 Jan 8 (1): 785. Sasaki Mariko, Harada Sei, Kawasaki Yumiko, Watanabe Miki, Ito Hidemi, Tanaka Hideo, Takeuchi Ayano, Tsubota Kazuo, Takebayashi Toru, Nishiwaki Yuji, Kawasaki R |
| Endogenous metabolites-mediated communication between OAT1/OAT3 and OATP1B1 may explain the association between SLCO1B1 SNPs and methotrexate toxicity. Clinical pharmacology and therapeutics 2017 Dec . Martinez David, Muhrez Kienana, Woillard Jean-Baptiste, Berthelot Aline, Gyan Emmanuel, Choquet Sylvain, Andrès Christian R, Marquet Pierre, Barin-Le Guellec Chant |
| Sphingolipid Metabolic Pathway Impacts Thiazide Diuretics Blood Pressure Response: Insights From Genomics, Metabolomics, and Lipidomics. Journal of the American Heart Association 2017 Dec 7 (1): . Shahin Mohamed H, Gong Yan, Frye Reginald F, Rotroff Daniel M, Beitelshees Amber L, Baillie Rebecca A, Chapman Arlene B, Gums John G, Turner Stephen T, Boerwinkle Eric, Motsinger-Reif Alison, Fiehn Oliver, Cooper-DeHoff Rhonda M, Han Xianlin, Kaddurah-Daouk Rima, Johnson Julie |
| Identification of SPOP related metabolic pathways in prostate cancer. Oncotarget 2017 Nov 8 (61): 103032-103046. Yan Min, Qi Huan, Li Jia, Ye Guozhu, Shao Yaping, Li Tongming, Liu Jing, Piao Hai-Long, Xu Guowa |
| Sexual dimorphism in glioma glycolysis underlies sex differences in survival. JCI insight 2017 Aug 2 (15): . Ippolito Joseph E, Yim Aldrin Kay-Yuen, Luo Jingqin, Chinnaiyan Prakash, Rubin Joshua |
| Genetic variants including markers from the exome chip and metabolite traits of type 2 diabetes. Scientific reports 2017 Jul 7 (1): 6037. Jäger Susanne, Wahl Simone, Kröger Janine, Sharma Sapna, Hoffmann Per, Floegel Anna, Pischon Tobias, Prehn Cornelia, Adamski Jerzy, Müller-Nurasyid Martina, Waldenberger Melanie, Strauch Konstantin, Peters Annette, Gieger Christian, Suhre Karsten, Grallert Harald, Boeing Heiner, Schulze Matthias B, Meidtner Kari |
| A pilot study identifying a potential plasma biomarker for determining EGFR mutations in exons 19 or 21 in lung cancer patients. Molecular medicine reports 2017 Jun 15 (6): 4155-4161. Pamungkas Aryo D, Medriano Carl A, Sim Eunjung, Lee Sungyong, Park Youngja |
| Urinary metabolites along with common and rare genetic variations are associated with incident chronic kidney disease. Kidney international 2017 Mar . McMahon Gearoid M, Hwang Shih-Jen, Clish Clary B, Tin Adrienne, Yang Qiong, Larson Martin G, Rhee Eugene P, Li Man, , Levy Daniel, O'Donnell Christopher J, Coresh Josef, Young J Hunter, Gerszten Robert E, Fox Caroline |
| Mediterranean diet-gene interactions: a targeted metabolomics study in Greek-Cypriot women. Molecular nutrition & food research 2016 Nov . Kakkoura Maria G, Sokratous Kleitos, Demetriou Christiana A, Loizidou Maria A, Loucaides Giorgos, Kakouri Eleni, Hadjisavvas Andreas, Kyriacou Kyriac |
| Why Are Omics Technologies Important to Understanding the Role of Nutrition in Inflammatory Bowel Diseases? International journal of molecular sciences 2016 Oct 17 (10): . Ferguson Lynnette R, Barnett Matthew P |
| Human Genetic Variation, Sport and Exercise Medicine, and Achilles Tendinopathy: Role for Angiogenesis-Associated Genes. Omics : a journal of integrative biology 2016 Sep 20 (9): 520-7. Rahim Masouda, El Khoury Louis Y, Raleigh Stuart M, Ribbans William J, Posthumus Michael, Collins Malcolm, September Alison |
| Novel plasma biomarker of atenolol-induced hyperglycemia identified through a metabolomics-genomics integrative approach. Metabolomics : open access 2016 Aug 12 . de Oliveira Felipe A, Shahin Mohamed H, Gong Yan, McDonough Caitrin W, Beitelshees Amber L, Gums John G, Chapman Arlene B, Boerwinkle Eric, Turner Stephen T, Frye Reginald F, Fiehn Oliver, Kaddurah-Daouk Rima, Johnson Julie A, Cooper-DeHoff Rhonda |
| A Genetic Response Score for Hydrochlorothiazide Use: Insights From Genomics and Metabolomics Integration. Hypertension 2016 Jul . Shahin Mohamed H, Gong Yan, McDonough Caitrin W, Rotroff Daniel M, Beitelshees Amber L, Garrett Timothy J, Gums John G, Motsinger-Reif Alison, Chapman Arlene B, Turner Stephen T, Boerwinkle Eric, Frye Reginald F, Fiehn Oliver, Cooper-DeHoff Rhonda M, Kaddurah-Daouk Rima, Johnson Julie |
| Genomics, Telomere Length, Epigenetics, and Metabolomics in the Nurses' Health Studies. American journal of public health 2016 Jul e1-e6. Townsend Mary K, Aschard Hugues, De Vivo Immaculata, Michels Karin B, Kraft Pet |
| Human blood cell levels of 5-hydroxymethylcytosine (5hmC) decline with age, partly related to acquired mutations in TET2. Experimental hematology 2016 Jul . Buscarlet Manuel, Tessier Alain, Provost Sylvie, Mollica Luigina, Busque Lambe |
| Identification of Rare Variants in Metabolites of the Carnitine Pathway by Whole Genome Sequencing Analysis. Genetic epidemiology 2016 Jun . Yazdani Akram, Yazdani Azam, Liu Xiaoming, Boerwinkle Er |
| Non-invasive Detection of Non-alcoholic Steatohepatitis Using Clinical Markers and Circulating Levels of Lipids and Metabolites. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2016 Jun . Zhou You, Oreši? Matej, Leivonen Marja, Gopalacharyulu Peddinti, Hyysalo Jenni, Arola Johanna, Verrijken An, Francque Sven, Van Gaal Luc, Hyötyläinen Tuulia, Yki-Järvinen Hanne |
| Attention-deficit hyperactivity disorder in adults: A systematic review and meta-analysis of genetic, pharmacogenetic and biochemical studies. Molecular psychiatry 2016 May . Bonvicini C, Faraone S V, Scassellati |
| Gene-gene and gene-environment interactions on risk of male infertility: Focus on the metabolites. Environment international 2016 Mar 91 188-195. Hu Weiyue, Chen Minjian, Wu Wei, Lu Jing, Zhao Dan, Pan Feng, Lu Chuncheng, Xia Yankai, Hu Lingqing, Chen Daozhen, Sha Jiahao, Wang Xin |
Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.  Nature communications 2016 Mar 7 11122. Kettunen Johannes, Demirkan Ay?e, Würtz Peter, Draisma Harmen H M, Haller Toomas, Rawal Rajesh, Vaarhorst Anika, Kangas Antti J, Lyytikäinen Leo-Pekka, Pirinen Matti, Pool René, Sarin Antti-Pekka, Soininen Pasi, Tukiainen Taru, Wang Qin, Tiainen Mika, Tynkkynen Tuulia, Amin Najaf, Zeller Tanja, Beekman Marian, Deelen Joris, van Dijk Ko Willems, Esko Tõnu, Hottenga Jouke-Jan, van Leeuwen Elisabeth M, Lehtimäki Terho, Mihailov Evelin, Rose Richard J, de Craen Anton J M, Gieger Christian, Kähönen Mika, Perola Markus, Blankenberg Stefan, Savolainen Markku J, Verhoeven Aswin, Viikari Jorma, Willemsen Gonneke, Boomsma Dorret I, van Duijn Cornelia M, Eriksson Johan, Jula Antti, Järvelin Marjo-Riitta, Kaprio Jaakko, Metspalu Andres, Raitakari Olli, Salomaa Veikko, Slagboom P Eline, Waldenberger Melanie, Ripatti Samuli, Ala-Korpela Mi |
| TSPAN5, ERICH3 and selective serotonin reuptake inhibitors in major depressive disorder: pharmacometabolomics-informed pharmacogenomics. Molecular psychiatry 2016 Feb . Gupta M, Neavin D, Liu D, Biernacka J, Hall-Flavin D, Bobo W V, Frye M A, Skime M, Jenkins G D, Batzler A, Kalari K, Matson W, Bhasin S S, Zhu H, Mushiroda T, Nakamura Y, Kubo M, Wang L, Kaddurah-Daouk R, Weinshilboum R |
| Genome-wide association study and targeted metabolomics identifies sex-specific association of CPS1 with coronary artery disease. Nature communications 2016 Jan 7 10558. Hartiala Jaana A, Tang W H Wilson, Wang Zeneng, Crow Amanda L, Stewart Alexandre F R, Roberts Robert, McPherson Ruth, Erdmann Jeanette, Willenborg Christina, Hazen Stanley L, Allayee Hoom |
| An exome array study of the plasma metabolome. Nature communications 2016 7 12360. Rhee Eugene P, Yang Qiong, Yu Bing, Liu Xuan, Cheng Susan, Deik Amy, Pierce Kerry A, Bullock Kevin, Ho Jennifer E, Levy Daniel, Florez Jose C, Kathiresan Sek, Larson Martin G, Vasan Ramachandran S, Clish Clary B, Wang Thomas J, Boerwinkle Eric, O'Donnell Christopher J, Gerszten Robert |
| Are there possible associations between MnSOD and GPx1 gene variants for laryngeal cancer risk or disease progression? Cellular and molecular biology (Noisy-le-Grand, France) 2016 62 (5): 25-30. Coskun C, Verim A, Farooqi A A, Turan S, Mezani B, Kucukhuseyin O, Tolgahan Hakan M, Ergen A, Yaylim |
| Association of Metabolites with Obesity and Type 2 Diabetes Based on FTO Genotype. PloS one 2016 11 (6): e0156612. Kim Yeon-Jung, Lee Heun-Sik, Kim Yun Kyoung, Park Suyeon, Kim Jeong-Min, Yun Jun Ho, Yu Ho-Yeong, Kim Bong- |
| Genomic and Metabolomic Profile Associated to Clustering of Cardio-Metabolic Risk Factors. PloS one 2016 11 (9): e0160656. Marrachelli Vannina G, Rentero Pilar, Mansego María L, Morales Jose Manuel, Galan Inma, Pardo-Tendero Mercedes, Martinez Fernando, Martin-Escudero Juan Carlos, Briongos Laisa, Chaves Felipe Javier, Redon Josep, Monleon Dani |
| The Pharmacogenetic Footprint of ACE Inhibition: A Population-Based Metabolomics Study. PloS one 2016 11 (4): e0153163. Altmaier Elisabeth, Menni Cristina, Heier Margit, Meisinger Christa, Thorand Barbara, Quell Jan, Kobl Michael, Römisch-Margl Werner, Valdes Ana M, Mangino Massimo, Waldenberger Melanie, Strauch Konstantin, Illig Thomas, Adamski Jerzy, Spector Tim, Gieger Christian, Suhre Karsten, Kastenmüller Ga |
| Variant rs10911021 that associates with coronary heart disease in type 2 diabetes, is associated with lower concentrations of circulating HDL cholesterol and large HDL particles but not with amino acids. Cardiovascular diabetology 2016 15 (1): 115. Beaney Katherine E, Cooper Jackie A, McLachlan Stela, Wannamethee S Goya, Jefferis Barbara J, Whincup Peter, Ben-Shlomo Yoav, Price Jacqueline F, Kumari Meena, Wong Andrew, Ong Ken, Hardy Rebecca, Kuh Diana, Kivimaki Mika, Kangas Antti J, Soininen Pasi, Ala-Korpela Mika, Drenos Fotios, Humphries Steve E, |
| An omics investigation into chronic widespread musculoskeletal pain reveals epiandrosterone sulfate as a potential biomarker. Pain 2015 Oct 156 (10): 1845-51. Livshits Gregory, Macgregor Alexander J, Gieger Christian, Malkin Ida, Moayyeri Alireza, Grallert Harald, Emeny Rebecca T, Spector Tim, Kastenmüller Gabi, Williams Frances M |
| Genome-wide association study of triglyceride response to a high-fat meal among participants of the NHLBI Genetics of Lipid Lowering Drugs and Diet Network (GOLDN). Metabolism: clinical and experimental 2015 Oct 64 (10): 1359-71. Wojczynski Mary K, Parnell Laurence D, Pollin Toni I, Lai Chao Q, Feitosa Mary F, O'Connell Jeff R, Frazier-Wood Alexis C, Gibson Quince, Aslibekyan Stella, Ryan Kathy A, Province Michael A, Tiwari Hemant K, Ordovas Jose M, Shuldiner Alan R, Arnett Donna K, Borecki Ingrid |
| A Pharmacometabonomic Approach To Predicting Metabolic Phenotypes and Pharmacokinetic Parameters of Atorvastatin in Healthy Volunteers. Journal of proteome research 2015 Sep 14 (9): 3970-81. Huang Qing, Aa Jiye, Jia Huning, Xin Xiaoqing, Tao Chunlei, Liu Linsheng, Zou Bingjie, Song Qinxin, Shi Jian, Cao Bei, Yong Yonghong, Wang Guangji, Zhou Guoh |
| Genome-Wide Association Study with Targeted and Non-targeted NMR Metabolomics Identifies 15 Novel Loci of Urinary Human Metabolic Individuality. PLoS genetics 2015 Sep 11 (9): e1005487. Raffler Johannes, Friedrich Nele, Arnold Matthias, Kacprowski Tim, Rueedi Rico, Altmaier Elisabeth, Bergmann Sven, Budde Kathrin, Gieger Christian, Homuth Georg, Pietzner Maik, Römisch-Margl Werner, Strauch Konstantin, Völzke Henry, Waldenberger Melanie, Wallaschofski Henri, Nauck Matthias, Völker Uwe, Kastenmüller Gabi, Suhre Karst |
| Mitochondrial Citrate Transporter-dependent Metabolic Signature in the 22q11.2 Deletion Syndrome. The Journal of biological chemistry 2015 Sep 290 (38): 23240-53. Napoli Eleonora, Tassone Flora, Wong Sarah, Angkustsiri Kathleen, Simon Tony J, Song Gyu, Giulivi Cecil |
| Dimethylglycine Deficiency and the Development of Diabetes. Diabetes 2015 Aug 64 (8): 3010-6. Magnusson Martin, Wang Thomas J, Clish Clary, Engström Gunnar, Nilsson Peter, Gerszten Robert E, Melander Ol |
| Nonadditive Effects of Genes in Human Metabolomics. Genetics 2015 Jul 200 (3): 707-18. Tsepilov Yakov A, Shin So-Youn, Soranzo Nicole, Spector Tim D, Prehn Cornelia, Adamski Jerzy, Kastenmüller Gabi, Wang-Sattler Rui, Strauch Konstantin, Gieger Christian, Aulchenko Yurii S, Ried Janina |
| 6C.04: INTEGRATED SNP ANALYSIS AND METABOLOMIC PROFILES OF METABOLIC SYNDROME. Journal of hypertension 2015 Jun 33 Suppl 1 e80. Marrachelli V, Monleon D, Morales J M, Rentero P, Martínez F, Chaves F J, Martin-Escudero J C, Redon |
| Genomics and metabolomics of muscular mass in community-based sample of UK females. European journal of human genetics : EJHG 2015 Apr . Korostishevsky Michael, Steves Claire J, Malkin Ida, Spector Timothy, Williams Frances Mk, Livshits Grego |
| Identification of novel biomarkers for Parkinson's disease by metabolomic technologies. Journal of neurology, neurosurgery, and psychiatry 2015 Mar . Hatano Taku, Saiki Shinji, Okuzumi Ayami, Mohney Robert P, Hattori Nobuta |
| Genome-wide association study of NMDA receptor coagonists in human cerebrospinal fluid and plasma. Molecular psychiatry 2015 Feb . Luykx J J, Bakker S C, Visser W F, Verhoeven-Duif N, Buizer-Voskamp J E, den Heijer J M, Boks M P M, Sul J H, Eskin E, Ori A P, Cantor R M, Vorstman J, Strengman E, DeYoung J, Kappen T H, Pariama E, van Dongen E P A, Borgdorff P, Bruins P, de Koning T J, Kahn R S, Ophoff R |
| [Genomic, proteomic and metabolomic predictors of nonalcoholic fatty liver disease development in obese patients. Part I]. Voprosy pitaniia 2015 84 (4): 18-24. Chernyak O O, Sentsova T B, Vorozhko I V, Tutelyan V A, Gapparova K M, Isakov V |
| Multi-omic profiles of human non-alcoholic fatty liver disease tissue highlight heterogenic phenotypes. Scientific data 2015 2 150068. Wruck Wasco, Kashofer Karl, Rehman Samrina, Daskalaki Andriani, Berg Daniela, Gralka Ewa, Jozefczuk Justyna, Drews Katharina, Pandey Vikash, Regenbrecht Christian, Wierling Christoph, Turano Paola, Korf Ulrike, Zatloukal Kurt, Lehrach Hans, Westerhoff Hans V, Adjaye Jam |
| The ACTN3 R577X Polymorphism Is Associated with Cardiometabolic Fitness in Healthy Young Adults. PloS one 2015 10 (6): e0130644. Deschamps Chelsea L, Connors Kimberly E, Klein Matthias S, Johnsen Virginia L, Shearer Jane, Vogel Hans J, Devaney Joseph M, Gordish-Dressman Heather, Many Gina M, Barfield Whitney, Hoffman Eric P, Kraus William E, Hittel Dustin |
| Interactions between genetic variants and dietary lipid composition: effects on circulating LDL cholesterol in children. The American journal of clinical nutrition 2014 Dec 100 (6): 1569-77. Ahola-Olli Ari V, Pitkänen Niina, Kettunen Johannes, Oikonen Mervi K, Mikkilä Vera, Lehtimäki Terho, Kähönen Mika, Pahkala Katja, Niinikoski Harri, Kangas Antti J, Soininen Pasi, Ala-Korpela Mika, Viikari Jorma S, Rönnemaa Tapani, Simell Olli, Raitakari Olli |
| Metabolomics reveals the sex-specific effects of the SORT1 low-density lipoprotein cholesterol locus in healthy young adults. Journal of proteome research 2014 Nov 13 (11): 5063-70. Klein Matthias S, Connors Kimberly E, Shearer Jane, Vogel Hans J, Hittel Dustin |
| Novel genetic associations with serum level metabolites identified by phenotype set enrichment analyses. Human molecular genetics 2014 Nov 23 (21): 5847-57. Ried Janina S, Shin So-Youn, Krumsiek Jan, Illig Thomas, Theis Fabian J, Spector Tim D, Adamski Jerzy, Wichmann H-Erich, Strauch Konstantin, Soranzo Nicole, Suhre Karsten, Gieger Christi |
| Assessing multivariate gene-metabolome associations with rare variants using Bayesian reduced rank regression. Bioinformatics (Oxford, England) 2014 Jul 30 (14): 2026-34. Marttinen Pekka, Pirinen Matti, Sarin Antti-Pekka, Gillberg Jussi, Kettunen Johannes, Surakka Ida, Kangas Antti J, Soininen Pasi, O'Reilly Paul, Kaakinen Marika, Kähönen Mika, Lehtimäki Terho, Ala-Korpela Mika, Raitakari Olli T, Salomaa Veikko, Järvelin Marjo-Riitta, Ripatti Samuli, Kaski Samu |
| An atlas of genetic influences on human blood metabolites. Nature genetics 2014 Jun 46 (6): 543-50. Shin So-Youn, Fauman Eric B, Petersen Ann-Kristin, Krumsiek Jan, Santos Rita, Huang Jie, Arnold Matthias, Erte Idil, Forgetta Vincenzo, Yang Tsun-Po, Walter Klaudia, Menni Cristina, Chen Lu, Vasquez Louella, Valdes Ana M, Hyde Craig L, Wang Vicky, Ziemek Daniel, Roberts Phoebe, Xi Li, Grundberg Elin, , Waldenberger Melanie, Richards J Brent, Mohney Robert P, Milburn Michael V, John Sally L, Trimmer Jeff, Theis Fabian J, Overington John P, Suhre Karsten, Brosnan M Julia, Gieger Christian, Kastenmüller Gabi, Spector Tim D, Soranzo Nico |
| Is diabetes mellitus-linked amino acid signature associated with ?-blocker-induced impaired fasting glucose? Circulation. Cardiovascular genetics 2014 Apr 7 (2): 199-205. Cooper-Dehoff Rhonda M, Hou Wei, Weng Liming, Baillie Rebecca A, Beitelshees Amber L, Gong Yan, Shahin Mohamed H A, Turner Stephen T, Chapman Arlene, Gums John G, Boyle Stephen H, Zhu Hongjie, Wikoff William R, Boerwinkle Eric, Fiehn Oliver, Frye Reginald F, Kaddurah-Daouk Rima, Johnson Julie |
| Association of tardive dyskinesia with variation in CYP2D6: Is there a role for active metabolites? Journal of psychopharmacology (Oxford, England) 2014 Mar 28 (7): 665-670. Koola Maju M, Tsapakis Evangelia M, Wright Padraig, Smith Shubulade, Kerwin Rip Robert W, Nugent Katie L, Aitchison Katherine |
| Genome-wide association study of metabolic traits reveals novel gene-metabolite-disease links. PLoS genetics 2014 Feb 10 (2): e1004132. Rueedi Rico, Ledda Mirko, Nicholls Andrew W, Salek Reza M, Marques-Vidal Pedro, Morya Edgard, Sameshima Koichi, Montoliu Ivan, Da Silva Laeticia, Collino Sebastiano, Martin François-Pierre, Rezzi Serge, Steinbeck Christoph, Waterworth Dawn M, Waeber Gérard, Vollenweider Peter, Beckmann Jacques S, Le Coutre Johannes, Mooser Vincent, Bergmann Sven, Genick Ulrich K, Kutalik Zolt |
| Clinical and non-targeted metabolomic profiling of homozygous carriers of Transcription Factor 7-like 2 variant rs7903146. Scientific reports 2014 4 5296. Wagner Robert, Li Jia, Kenar Erhan, Kohlbacher Oliver, Machicao Fausto, Häring Hans-Ulrich, Fritsche Andreas, Xu Guowang, Lehmann Rain |
| Genomic and metabolomic profile associated to microalbuminuria. PloS one 2014 9 (2): e98227. Marrachelli Vannina G, Monleon Daniel, Rentero Pilar, Mansego María L, Morales Jose Manuel, Galan Inma, Segura Remedios, Martinez Fernando, Martin-Escudero Juan Carlos, Briongos Laisa, Marin Pablo, Lliso Gloria, Chaves Felipe Javier, Redon Jos |
| Genome-wide association study of a heart failure related metabolomic profile among African Americans in the Atherosclerosis Risk in Communities (ARIC) study. Genetic epidemiology 2013 Dec 37 (8): 840-5. Yu Bing, Zheng Yan, Alexander Danny, Manolio Teri A, Alonso Alvaro, Nettleton Jennifer A, Boerwinkle Er |
| Evaluation of endogenous metabolic markers of hepatic CYP3A activity using metabolic profiling and midazolam clearance. Clinical pharmacology and therapeutics 2013 Nov 94 (5): 601-9. Shin K-H, Choi M H, Lim K S, Yu K-S, Jang I-J, Cho J |
| Pharmacometabolomics reveals racial differences in response to atenolol treatment. PloS one 2013 8 (3): e57639. Wikoff William R, Frye Reginald F, Zhu Hongjie, Gong Yan, Boyle Stephen, Churchill Erik, Cooper-Dehoff Rhonda M, Beitelshees Amber L, Chapman Arlene B, Fiehn Oliver, Johnson Julie A, Kaddurah-Daouk Rima, |
| A Genome-Wide Assessment of Variability in Human Serum Metabolism. Human mutation 2012 Dec . Hong MG, Karlsson R, Magnusson PK, Lewis MR, Isaacs W, Zheng LS, Xu J, Grönberg H, Ingelsson E, Pawitan Y, Broeckling C, Prenni JE, Wiklund F, Prince JA |
| Detailed metabolic and genetic characterization reveals new associations for 30 known lipid loci. Human molecular genetics 2012 Mar 21 (6): 1444-55. Tukiainen Taru, Kettunen Johannes, Kangas Antti J, Lyytikäinen Leo-Pekka, Soininen Pasi, Sarin Antti-Pekka, Tikkanen Emmi, O'Reilly Paul F, Savolainen Markku J, Kaski Kimmo, Pouta Anneli, Jula Antti, Lehtimäki Terho, Kähönen Mika, Viikari Jorma, Taskinen Marja-Riitta, Jauhiainen Matti, Eriksson Johan G, Raitakari Olli, Salomaa Veikko, Järvelin Marjo-Riitta, Perola Markus, Palotie Aarno, Ala-Korpela Mika, Ripatti Samu |
| Candidate proteins, metabolites and transcripts in the Biomarkers for Spinal Muscular Atrophy (BforSMA) clinical study. PloS one 2012 7 (4): e35462. Finkel Richard S, Crawford Thomas O, Swoboda Kathryn J, Kaufmann Petra, Juhasz Peter, Li Xiaohong, Guo Yu, Li Rebecca H, Trachtenberg Felicia, Forrest Suzanne J, Kobayashi Dione T, Chen Karen S, Joyce Cynthia L, Plasterer Thomas, |
| Mining the unknown: a systems approach to metabolite identification combining genetic and metabolic information. PLoS genetics 2012 8 (10): e1003005. Krumsiek Jan, Suhre Karsten, Evans Anne M, Mitchell Matthew W, Mohney Robert P, Milburn Michael V, Wägele Brigitte, Römisch-Margl Werner, Illig Thomas, Adamski Jerzy, Gieger Christian, Theis Fabian J, Kastenmüller Ga |
| Schizophrenia shows a unique metabolomics signature in plasma. Translational psychiatry 2012 2 e149. He Y, Yu Z, Giegling I, Xie L, Hartmann A M, Prehn C, Adamski J, Kahn R, Li Y, Illig T, Wang-Sattler R, Rujescu |
| A genome-wide metabolic QTL analysis in Europeans implicates two loci shaped by recent positive selection. PLoS genetics 2011 Sep 7 (9): e1002270. Nicholson George, Rantalainen Mattias, Li Jia V, Maher Anthony D, Malmodin Daniel, Ahmadi Kourosh R, Faber Johan H, Barrett Amy, Min Josine L, Rayner N William, Toft Henrik, Krestyaninova Maria, Viksna Juris, Neogi Sudeshna Guha, Dumas Marc-Emmanuel, Sarkans Ugis, , Donnelly Peter, Illig Thomas, Adamski Jerzy, Suhre Karsten, Allen Maxine, Zondervan Krina T, Spector Tim D, Nicholson Jeremy K, Lindon John C, Baunsgaard Dorrit, Holmes Elaine, McCarthy Mark I, Holmes Chris |
| Human metabolic individuality in biomedical and pharmaceutical research. Nature 2011 Sep 477 (7362): 54-60. Suhre Karsten, Shin So-Youn, Petersen Ann-Kristin, Mohney Robert P, Meredith David, Wägele Brigitte, Altmaier Elisabeth, , Deloukas Panos, Erdmann Jeanette, Grundberg Elin, Hammond Christopher J, de Angelis Martin Hrabé, Kastenmüller Gabi, Köttgen Anna, Kronenberg Florian, Mangino Massimo, Meisinger Christa, Meitinger Thomas, Mewes Hans-Werner, Milburn Michael V, Prehn Cornelia, Raffler Johannes, Ried Janina S, Römisch-Margl Werner, Samani Nilesh J, Small Kerrin S, Wichmann H-Erich, Zhai Guangju, Illig Thomas, Spector Tim D, Adamski Jerzy, Soranzo Nicole, Gieger Christi |
| Enteric microbiome metabolites correlate with response to simvastatin treatment. PloS one 2011 6 (10): e25482. Kaddurah-Daouk Rima, Baillie Rebecca A, Zhu Hongjie, Zeng Zhao-Bang, Wiest Michelle M, Nguyen Uyen Thao, Wojnoonski Katie, Watkins Steven M, Trupp Miles, Krauss Ronald |
| Metabolomic profiling in LRRK2-related Parkinson's disease. PloS one 2009 4 (10): e7551. Johansen Krisztina K, Wang Lei, Aasly Jan O, White Linda R, Matson Wayne R, Henchcliffe Claire, Beal M Flint, Bogdanov Mikha |
| Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum. PLoS genetics 2008 Nov 4 (11): e1000282. Gieger Christian, Geistlinger Ludwig, Altmaier Elisabeth, Hrabé de Angelis Martin, Kronenberg Florian, Meitinger Thomas, Mewes Hans-Werner, Wichmann H-Erich, Weinberger Klaus M, Adamski Jerzy, Illig Thomas, Suhre Karst |
| Integration of targeted metabolomics and transcriptomics identifies deregulation of phosphatidylcholine metabolism in Huntington's disease peripheral blood samples. Metabolomics : Official journal of the Metabolomic Society 0 12 137. Mastrokolias Anastasios, Pool Rene, Mina Eleni, Hettne Kristina M, van Duijn Erik, van der Mast Roos C, van Ommen GertJan, 't Hoen Peter A C, Prehn Cornelia, Adamski Jerzy, van Roon-Mom Wille |
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