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Title : Cancer Genomics - Cancer PHGKB -
link : Cancer Genomics - Cancer PHGKB -

Cancer Genomics - Cancer PHGKB -

Specific PHGKB|Cancer|PHGKB

Cancer Genomics

- Cancer PHGKB -

From Tier Table Database

CDC Office of Public Health Genomics (OPHG) conducts horizon scanning (a systematic research method to find and follow novel technologies appearing in the literature) to identify and track the progress of genomic tests as they move from research into clinical and public health practice. As an aid in organizing horizon scanning results, OPHG ranks genomic tests, and family health history applications, by levels of evidence. See detail.

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Disease/Disorder	Test or Application	Intended Use	Tier Classified	Detail
Personal or family history of breast cancer or ovarian cancer	Genetic counseling	Risk prediction for hereditary breast and ovarian cancer syndrome	Tier 1
Ovarian epithelial cancer (including fallopian tube cancer or primary peritoneal cancer)	Genetic counseling	Risk prediction for hereditary breast and ovarian cancer syndrome	Tier 1
Ovarian cancer	Next generation sequencing and analysis of BRCA1 and BRCA2 using FoundationFocus CDxBRCA Assay(TM)	Pharmacogenomic, to help in identification of ovarian cancer patients for whom rucaparib treatment is being considered	Tier 1
BRCA-related cancer; hereditary breast and ovarian cancer	Consideration of multigene BRCA1/BRCA2 testing, following specified test criteria, risk assessment and counseling*	Breast/ovarian cancer risk prediction	Tier 1
BRCA-related cancer; hereditary breast and ovarian cancer	Consideration of comprehensive BRCA1/BRCA2 testing of family member with greatest likelihood of mutation, following specified test criteria, risk assessment and counseling*	Breast/ovarian cancer risk prediction	Tier 1

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