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Title : Heart disease :: Updates on Specific Diseases
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Heart disease :: Updates on Specific Diseases

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From Tier Table Database

CDC Office of Public Health Genomics (OPHG) conducts horizon scanning (a systematic research method to find and follow novel technologies appearing in the literature) to identify and track the progress of genomic tests as they move from research into clinical and public health practice. As an aid in organizing horizon scanning results, OPHG ranks genomic tests, and family health history applications, by levels of evidence. See detail.

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Disease/Disorder	Test or Application	Intended Use	Tier Classified	Detail
Hypertrophic cardiomyopathy (HCM) - symptoms and signs of disease suggesting specific causes of HCM	Genetic testing (including analysis of most frequently implicated sarcomere protein genes)	Confirm diagnosis of HCM	Tier 1
Hypertrophic cardiomyopathy (HCM)	Genetic testing (including analysis of most frequently implicated sarcomere protein genes)	Enable cascade screening of relatives	Tier 1
Hypertrophic cardiomyopathy (HCM) that cannot be explained solely by non-genetic cause	Genetic counseling	Help patients understand and manage HCM	Tier 1
Acute coronary syndrome	CYP2C19	Pharmacogenomic for ticagrelor	Tier 2
Acute coronary syndrome managed with percutaneous coronary intervention	CYP2C19	Pharmacogenomic for prasugrel	Tier 2

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