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Title : Health News and Information - News Medical :: Genetics - Jan 11, 2018 Edition
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Health News and Information - News Medical :: Genetics - Jan 11, 2018 Edition

Health News and Information - News Medical

January 11, 2018     Genetics     The latest Genetics news from News Medical

Regeneron forms consortium to accelerate largest widely-available human sequencing resource   By the end of 2019, Regeneron plans to sequence the exomes of all 500,000 people within the UK Biobank resource, all with associated health records, creating an unprecedented resource linking human genetic variations to human biology and disease.       Research sheds light on role of epigenetics in placing egg cells into stasis   Keeping egg cells in stasis during childhood is a key part of female fertility. New research published today (1st January) in Nature Structural and Molecular Biology sheds some light on the role of epigenetics in placing egg cells into stasis.

Genetic differences can influence efficiency of medicines   Medicines do not follow the one size fits all principle, because genetic differences can influence their efficiency.         Sangamo and Pfizer partner for development of new zinc finger protein gene therapy to treat ALS   Sangamo Therapeutics, Inc. and Pfizer Inc. today announced a collaboration for the development of a potential gene therapy using zinc finger protein transcription factors (ZFP-TFs) to treat amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) linked to mutations of the C9ORF72 gene.         Polygenic risk score predicts early-onset heart disease risk   A risk score based on multiple genetic differences, or polygenic risk score, predicted significantly more cases of early-onset heart disease than standard tests for single genetic defects, according to new research in the American Heart Association's journal Circulation: Genomic and Precision Medicine.         Deciphering Antibodies with Next-Generation Protein Sequencing Technology   Mr. Mingjie Xie, MSc, MBA, is the co-founder and CEO of Rapid Novor Inc. He is a computer scientist by training andreceived his MSc degree from Western University in the field of bioinformatics. He received his MBA degree from Richard Ivey School of Business to pursue his interests in business. Prior to co-founding Rapid Novor Inc, Mingjie is the COO of a bioinformatics software company.         Why Should We Weigh Every Protein in the Human Body?   Our mission is to advance the measurement of human proteins with greater precision, to bring to the world the benefits of absolute molecular specificity when it comes to interrogating proteins at the molecular level.

Genetic Studies with S. cerevisiae and Mitotic Insights   Budding yeast are used extensively in genetics. Cdc28 in S. cerevisiae and cdc2 in S. pombe continue to provide useful insights into mitosis.       Genetic changes help mosquitoes to develop pesticide resistance   For decades, chemical pesticides have been the most important way of controlling insects like the Anopheles mosquito species that spreads malaria to humans.       UC Davis expert expresses caution on genetically engineered HSCs   In a commentary published in the Jan. 4 issue of the New England Journal of Medicine, UC Davis researcher William Murphy expressed cautious optimism about efforts to genetically engineer hematopoietic stem cells (HSCs) to temporarily resist cell death during transplantation.       Genetic labeling helps researchers track behavior of blood cells   By tagging bone marrow cells of mice with a genetic label, or barcode, researchers were able to track and describe the family tree of individual blood cells as they form in their natural environment.       Gene therapy with CAR T-cells could create long-term immunity from HIV   Through gene therapy, researchers engineered blood-forming stem cells (hematopoietic stem/progenitor cells, or HSPCs) to carry chimeric antigen receptor (CAR) genes to make cells that can detect and destroy HIV-infected cells.       UAB study shows missense mutations as key risk factor for severe symptoms of neurofibromatosis type 1   Research led by Ludwine Messiaen, Ph.D., professor of genetics at the University of Alabama at Birmingham, shows that missense mutations in a cluster of just five codons in the NF1 gene are an important risk factor for severe symptoms of the genetic disease neurofibromatosis type 1.       Knockout Mouse Project to Identify Gene Functions in vivo   The knockout mouse project (KOMP) will provide cumulative information about the genome of mouse knockouts for the generation of a repository.       Scientists show how alcohol exposure leads to permanent genetic damage   Scientists have shown how alcohol damages DNA in stem cells, helping to explain why drinking increases your risk of cancer, according to research part-funded by Cancer Research UK and published in Nature today (Wednesday).       Researchers discover genetic mechanism for resistance to immunotherapy drugs   An urgent question for cancer scientists is why immunotherapy achieves dramatic results in some cases but doesn't help most patients.       Researcher shows how rank order can be used to identify complex gene interactions   Genome sequencing has revolutionized genetics. It also requires new mathematical tools to help life scientists make sense of enormous amounts of data.       WPI professor receives Smith Family Foundation grant to explore biology of cancer cells   Amity Manning, assistant professor of biology and biotechnology, has received a three-year, $300,000 award from the Smith Family Awards Program for Excellence in Biomedical Research.       Scientists find gene that predisposes Greenlanders to obesity   Greenland is like many other countries struggling with overweight and obesity. Both environment and genetics play a role in development of obesity.       Cellular mechanism protects genes from damaging effects of mutation   Researchers at the University of Oxford have discovered that a cellular mechanism preferentially protects plant genes from the damaging effects of mutation.       Bielefeld scientists discover cause of initially unclear symptoms   The sequencing of the human genome has made it possible: nowadays scientists can discover potential disorders for which there are no known patients.       Study provides insight into how early-stage breast cancer progresses to invasive ductal carcinoma   A new genetic-based model may explain how a common form of early-stage breast cancer known as ductal carcinoma in situ progresses to a more invasive form of cancer say researchers at The University of Texas MD Anderson Cancer Center.

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